Impact of yogurt consumption on bone health markers in adults with or without osteoporosis: a systematic review and meta-analysis

Mayo, Baltasar and Malagón-Rojas, Jeadran and Agahi, Fojan and Frias, Juana and Künili, İbrahim Ender and Kütt, Mary-Liis and Mardon, Julie and Nikolovska Nedelkoska, Daniela and Parada, Mayra Alejandra and Torbica, Aleksandra and Bulmus Tuccar, Tugce and Yilmaz, Birsen and Bar, Cornelia and Harsa, Hayriye Sebnem and Chassard, Christophe and Praćer, Smilja and Vergères, Guy and Tamang, Jyoti Prakash (2025) Impact of yogurt consumption on bone health markers in adults with or without osteoporosis: a systematic review and meta-analysis. Front. Nutr..

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Abstract

Yogurt is a fermented dairy product widely recognized for its nutritional
value and potential health benefits, particularly due to its high content of
calcium, phosphorus, vitamins, and other bioactive compounds. Its purported
role in promoting bone health has attracted increasing attention, especially
among adults at risk of osteoporosis. However, the specific impact of yogurt
consumption on bone health remains controversial, as current evidence is
limited and often inconclusive. This systematic review and meta-analysis sought
to evaluate the exclusive effects of yogurt consumption on bone health in adults
with and without osteoporosis. Employing rigorous inclusion and exclusion
criteria and standardized methodologies, the study reviewed data from both
observational and clinical studies to assess the effect of yogurt consumption
on bone mineral density (BMD), fracture risk, and other bone health markers.
In addition, yogurt characteristics were documented in accordance with
EFSA guidelines, the possible bioactive components listed, and their potential
mechanism of action in relation to bone health discussed. Studies fitting the
inclusion and exclusion criteria (n = 12) were all observational, limiting the ability
to infer causality. The meta-analysis of cohort studies (n = 6) found no significant
association between yogurt consumption and hip fracture risk (HR = 1.01, 95%
Frontiers in Nutrition 01 frontiersin.org
Mayo et al. 10.3389/fnut.2025.1660505
CI: 0.96–1.07), while the observed positive effect on BMD was minimal and
clinically irrelevant (SMD = 0.009). Although some studies reported modest
improvements in BMD and bone biomarkers, the overall evidence remains
inconclusive, hindered by the heterogeneity in study designs and inconsistent
yogurt intake. In conclusion, current evidence does not support a significant
role of yogurt consumption in preventing fractures or improving BMD in adults.
Well-designed randomized controlled studies are needed to clarify its effects,
particularly in adults at risk of or with osteoporosis or osteopenia. In conclusion,
the effectiveness of yogurt as a primary strategy for enhancing bone health is
not fully substantiated by current data, though its inclusion within a balanced
diet may still offer benefits for bone health.
Systematic review registration: https://osf.io/, 10.17605/OSF.IO/ES2PM

Keywords: yogurt, fermented food, bone health, osteoporosis, osteopenia, systematic review,
meta-analysis

Item Type: Article
Subjects: Scientific Fields (Frascati) > Agricultural Sciences > Other agricultural sciences
Scientific Fields (Frascati) > Engineering and Technology > Other engineering and technologies
Divisions: Faculty of Technology and Technical Sciences
Depositing User: Mr Jordan Martinovski
Date Deposited: 24 Nov 2025 07:59
Last Modified: 24 Nov 2025 07:59
URI: https://eprints.uklo.edu.mk/id/eprint/11240

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