The Predictive Value of Aortic Stiffness in Detection of Acute Pulmonary Edema in Patients with Acute Dyspnoea

Avramovski, Petar and Sikole, Aleksandar (2017) The Predictive Value of Aortic Stiffness in Detection of Acute Pulmonary Edema in Patients with Acute Dyspnoea. EC Pulmonology and Respiratory Medicine, 5 (5). pp. 180-190.

Text 11. (2017) EC PULMONOLOGY & RESPIR, The Predictive value of stiffnes in detection of AP edema.pdf - Published Version Download (588kB)

Abstract

Objective: Acute pulmonary edema (APE) is potentially fatal cause of acute respiratory distress, often a result of acute decompensate
heart failure, a state with increased capillary pressure. The aim of this study was to find correlation between aortic stiffness and APE
in patients with acute dyspnoea, measuring the carotid – femoral pulse wave velocity (PWV) by Doppler ultrasonography.
Methods: We conducted PWV estimation at 47 hospitalized patients with acute dyspnoea aged 57.8 ± 9.4 years. Seventeen of them
had clinical signs of APE. The PWV was determined from time diversity propagation of the common carotid artery and femoral artery
by Doppler ultrasound.
Results: The mean PWV of the patients with or without APE was: 10.4 ± 1.64 m/s vs. 8.54 ± 1.51 m/s, respectively (p = 0.0005). We
found by receiver operating characteristic (ROC) a highest sensitivity of 76.47% and specificity of 80.0%, area under the ROC curve
(AUC = 0.803, p < 0.0001) at PWV cut-off = 9.1 m/s in the prediction of APE by PWV; by the multiple backward regression analysis,
we found βst = 0.1252 (p = 0.0010) and R2 = 0.3413. The positive and negative predictive values of PWV in prediction for APE are:
68.42% and 85.71%, respectively.
Conclusion: PWV as measure of arterial stiffness is predictor of left ventricle failure and APE in patients with acute dyspnoea, assessed
by simple, indirect, reproducible, and noninvasive evaluation of regional arterial stiffness.
Keywords: Acute Pulmonary Edema; Aortic Stiffness; Pulse Wave Velocity; Doppler Ultrasonography; Systolic Dysfunction

Item Type:	Article
Subjects:	Scientific Fields (Frascati) > Medical and Health Sciences > Clinical medicine
Divisions:	UKLO Network
Depositing User:	UKLO Mrezha
Date Deposited:	27 May 2024 05:56
Last Modified:	27 May 2024 05:56
URI:	https://eprints.uklo.edu.mk/id/eprint/9921

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