Cytokine Storm: A Threatening Challenge for COVID-19 Infected Patients

Avramovski, Petar (2021) Cytokine Storm: A Threatening Challenge for COVID-19 Infected Patients. EC Pulmonology and Respiratory medicine, 10 (5). pp. 1-4.

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21. (2021) EC PULMONOLOGY & RESP, Cytokine storm - A threating Challeng for COVID-19 infected Patients.pdf - Accepted Version

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Abstract

Cytokine storm (CV) is result of uncontrolled emission of cytokines under stimulation of infective agent. In fatal COVID-19 infection
is represented by acute respiratory distress syndrome (ARDS), pneumonia, hypercoagulation and multiorgan dysfunctions. The
characteristics of CS are capillaries leakage, tissue edema, which result with organ failure and shock, associated with excessive immune
response reaction which is triggered by activation of T-helper 1 reactions. Early detection of interleukin-6 (IL-6) in patients
with COVID-19 infection is helpful for early prediction of illness severity. Extracorporeal blood ultrafiltration by hemofilter AN69ST
(oXiris®) absorb IL-6, systemic hyperinflammation and coagulopathy and accelerate clinical recover of the COVID-19 patients.
Keywords: SARS-CoV-2; Acute Respiratory Distress Syndrome (ARDS); Cytokine Storm (CV); COVID-19

Item Type: Article
Subjects: Scientific Fields (Frascati) > Medical and Health Sciences > Basic medicine
Scientific Fields (Frascati) > Medical and Health Sciences > Clinical medicine
Divisions: UKLO Network
Depositing User: UKLO Mrezha
Date Deposited: 27 May 2024 05:56
Last Modified: 27 May 2024 05:56
URI: https://eprints.uklo.edu.mk/id/eprint/9919

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