Arsenic: Exposure through the food chain, toxicity, and toxicity reduction by nutritional compounds

Temelkovska, Katerina and Nikolovska Nedelkoska, Daniela and Pavlovska, Gorica and Blazevska, Tatjana and Delinikolova, Eleonora and Stojanovska, Tanja (2023) Arsenic: Exposure through the food chain, toxicity, and toxicity reduction by nutritional compounds. International Journal of Food Technology and Nutrition, 6 (11/12). pp. 32-42.

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Arsenic is widely distributed in the environment, including water, soil, and rocks. Arsenic enters the food chain through food contaminated by arsenic pesticides, crops irrigated with arsenic-contaminated water, or crops grown in arsenic-rich soil.
Among foods of plant origin, the highest concentrations of arsenic are found in rice, root and leafy vegetables. Arsenic can also be present in foods of animal origin, such as meat, fish, eggs, milk, and dairy products, as a result of animal exposure to arsenic through feed and drinking water. Arsenic causes acute and chronic toxicity through disruption of mitochondrial function and oxidative stress. Chronic exposure to arsenic leads to multisystem disease, neurotoxicity, hepatotoxicity, nephrotoxicity, carcinogenicity, and genotoxicity. The health risk in case of chronic exposure to arsenic is estimated according to the
calculation of: PTWI (Provisional Tolerable Weekly Intake), ER (Exposure rate), HQ (Hazard Quotient), and AELCR (Annual
excess lifetime cancer risk). It is of great importance to reduce the intake of arsenic in the population by monitoring important monitoring points, continuous analysis of food and drinking water, early diagnosis and intervention. Foods with a high content of antioxidants and bioactive compounds can reduce the toxic effect of arsenic. The most powerful medicinal plants for treating arsenic toxicity are garlic, turmeric, milk thistle, some dietary fibers, algae, green and black tea.

Keywords: arsenic, food, health risk, antioxidants

Item Type: Article
Subjects: Scientific Fields (Frascati) > Natural sciences > Biological sciences
Scientific Fields (Frascati) > Agricultural Sciences > Other agricultural sciences
Divisions: Faculty of Technology and Technical Sciences
Depositing User: Mr Jordan Martinovski
Date Deposited: 29 Mar 2024 10:24
Last Modified: 29 Mar 2024 10:24

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