CORRELATION OF NIACIN, NAD AND NADP CONCENTRATION IN BLOOD ASSOCIATED WITH LIPOLYSIS IN PERIPARTAL DAIRY COWS

HRISTOVSKA, TALIJA and CINCOVIĆ, MARKO and Dodovski, Petar and Karabolovski, Nikola and Dameski, Pance and Pejcinovska, Natasa and Zdraveski, Igor and Ristevski, Mimi and Angelovska, Maja and Jankulovska-Petkovska, Milena (2023) CORRELATION OF NIACIN, NAD AND NADP CONCENTRATION IN BLOOD ASSOCIATED WITH LIPOLYSIS IN PERIPARTAL DAIRY COWS. Horizons - International Scientific Journal, 1 (I).

Text (CORRELATION OF NIACIN, NAD AND NADP CONCENTRATION IN BLOOD ASSOCIATED WITH LIPOLYSIS IN PERIPARTAL DAIRY COWS) correlaton of niacin.pdf - Published Version Download (1MB)

Abstract

The aim of this study was to determine correlation between niacin application and concentration
of NAD and NADP in blood of cow in peripartal period, also their relation with NEFA
concentration was examined. Experiment included 30 cows (15 experimental and 15 animals in
control group). Application of niacin was conducted 2 weeks before and after calving. Nicotinic
acid was applicated per os with food, 120 grams per day per cow. Nicotinic acid was in rumen�unprotected form. The control group was not treated with nicotinic acid. Blood samples were
taken before the application of niacin, then on the day of calving and last sampling was done first
and second week after calving. Parameters such as NAD, NADP were determined. NAD and
NADP were determined using colorimetric ELISA method from erythrocytes lysates. Relation
between NAD, NADP and NAD/NADP thru experimental weeks was analyzed by Pearson's
correlation coefficient and simple linear regression model. Correlation and regression between
NAD, NADP and NAD/NADP with NEFA was calculated by same method. Results have showed
that cows that had niacin application have higher concentrations of NAD and NADP in blood 1
and 2 week after calving, NEFA was statistically lower in niacin group compared to the control
group in all weeks. Correlation between NAD and NADP was positive in niacin group and
negative in control group but significant correlation wasn’t founded between NAD and NADP and
NEFA in control and niacin group.
Key words: Cow; niacin; NAD; peripartal period; lipolysis

Item Type:	Article
Subjects:	Scientific Fields (Frascati) > Agricultural Sciences > Veterinary science
Divisions:	Faculty of Veterinary Medicine
Depositing User:	Mr Aleksandar Lozanovski
Date Deposited:	21 Feb 2024 10:01
Last Modified:	21 Feb 2024 10:01
URI:	https://eprints.uklo.edu.mk/id/eprint/9799

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