PRESENTATION OF THE RESULTS OF PREGNANCY CHROMOSOMAL ABNORMALITIES IN PHO CLINICAL HOSPITAL BITOLA FOR 2020 YEAR

Ilkovska, Biljana and Kotevska-Trifunova, Bisera (2022) PRESENTATION OF THE RESULTS OF PREGNANCY CHROMOSOMAL ABNORMALITIES IN PHO CLINICAL HOSPITAL BITOLA FOR 2020 YEAR. J Med Biochem, 41. p. 396. ISSN 1452-8258

Text JOURNAL OF MEDICAL BIOCHEMISTRY.pdf - Published Version Download (2MB)

Abstract

Genetic screening for chromosomopaty is performed in the first trimester of pregnancy by determining fetal nuchal translucency and pregnancy associated plasma protein A and free human chorionic gonadotropin hormone in maternal serum. This study was performed in 2020 year in Clinical Hospital Bitola. A total of 503 pregnant women were screened during the first trimester. The serum was separated and pregnancy associated plasma protein- A and free beta human chorionic gonadotrophin hormone were measured. The ultrasound scan included a full structural survey, and nuchal translucency. Risks for chromosomal abnormalities were calculated using the software Prisca - mathematical model which gives individual risks for trisomy 21, 18 and 13.Screening was carried out in 503 pregnancies. Median maternal age was 22,98 ±0.37 years (range: 16 to 42 years). Among the 503 pregnant women overall, 63 (13%) fetuses had an estimated
risk for trisomy 21 and trisomy 13/18. Of the 440 (87%) cases chromosomal abnormality was not found. Of utmost importance for pregnant woman and for the society is screened for chromosomal abnormalities in pregnancy and assessed the risk of Down syndrome, Edward syndrome and Patay. With this screening we are going to prevent their
occurrence and we’ll reduce the psychological and physical suffering of parents and society, especially in today’s modern society, where there are the most developed technologies in the industry and prevention is really possible!

Item Type:	Article
Subjects:	Scientific Fields (Frascati) > Medical and Health Sciences > Basic medicine
Divisions:	UKLO Network
Depositing User:	UKLO Mrezha
Date Deposited:	30 Jan 2024 08:03
Last Modified:	30 Jan 2024 08:03
URI:	https://eprints.uklo.edu.mk/id/eprint/9346

Actions (login required)

View Item