Correlation between serum levels of Anti CCP and RF in patients with joint pain

Ilkovska, Biljana and Kotevska-Trifunova, Bisera and Dimovski, Aleksandar (2019) Correlation between serum levels of Anti CCP and RF in patients with joint pain. Turkish Journal of Biochemistry,, 44 (S3).

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Abstract

OBJECTIVES:Rheumatoid arthritis affects 0.3% to 1% of the population. It is an autoimmune disease characterised by chronic synovial inflammation. Currently, the most well-known and established test is Anti CCP. It is extremely specific for rheumatoid arthritis, and is present early in disease, and predicts the erosive states of disease.
MATERIALS and METHODS:This prospective interventional study was performed between January 2019 and May 2019 in the PHO Clinical Hospital in Bitola. The study included 30 subjects - 21 females are with join pain and 9 males. The blood samples were taken after overnight fast (12 hours). Anti CCP
and RF were determined by Abbot Architect CI 4100 analyzer.
RESULTS:We found increased level of Anti CCP in 6 patients (4 females, 2 males), 11 patients have increased level of RF (7 females, 4 males), 3 patients have increased level of Anti CCP and RF (2 males, 1 women) and 16 patients have normal values of Anti CCP and RF. We found a great correlation in 19 patients between Anti CCP and RF
CONCLUSIONS:We found a significant correlation between RF and Anti CCP.
Keywords: anti-cyclic citrullinated peptides (anti-CCPs), rheumatoid factor, rheumatoid arthritis

Item Type:	Article
Subjects:	Scientific Fields (Frascati) > Medical and Health Sciences > Basic medicine Scientific Fields (Frascati) > Medical and Health Sciences > Clinical medicine Scientific Fields (Frascati) > Medical and Health Sciences > Health sciences
Divisions:	UKLO Network
Depositing User:	UKLO Mrezha
Date Deposited:	30 Jan 2024 08:03
Last Modified:	30 Jan 2024 08:03
URI:	https://eprints.uklo.edu.mk/id/eprint/9340

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