Elevated Serum Hepcidin and Ferritin Levels in Patients With Metabolic Syndrom in Macedonian Population

Ilkovska, Biljana and Kotevska-Trifunova, Bisera and Trifunov, Georgi (2015) Elevated Serum Hepcidin and Ferritin Levels in Patients With Metabolic Syndrom in Macedonian Population. INDIAN JOURNAL OF APPLIED RESEARCH, 5 (8). pp. 267-270. ISSN 2249-555X

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Abstract

The metabolic syndrome is a condition highly prevalent in western countries. The serum ferritin concentration
reflects iron stores in the body. In the last fifteen years, hepcidin was established as the key ironregulatory
hormone, closely related with metabolic syndrom. Aim of this study is to find еlevated serum hepcidin and
ferritin levels in patients with metabolic syndrom in Macedonian population.The analysed group consisted of 240 subjects
– 50% of them with metabolic syndrome and 50% control group. Hepcidin levels were measured with ELISA kit
(DRG Hepcidin-25 bioactive, Marburg). Мetabolic syndrome subjects have significantly higher serum levels of both ferritin
and hepcidin as compared to subjects in control group.The concentration of serum hepcidine and ferritin are associated
with gender, males had higher levels compared to females for both groups-control and group with metabolic
syndrom.

Item Type:	Article
Subjects:	Scientific Fields (Frascati) > Medical and Health Sciences > Basic medicine Scientific Fields (Frascati) > Medical and Health Sciences > Health sciences
Divisions:	UKLO Network
Depositing User:	UKLO Mrezha
Date Deposited:	30 Jan 2024 08:04
Last Modified:	30 Jan 2024 08:04
URI:	https://eprints.uklo.edu.mk/id/eprint/9334

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