Evaluation of bactericidal activity of selected wild macrofungi extracts against Escherichia coli

Nikolovska-Nedelkoska, Daniela and Kalevska, Tatjana and Atanasova-Pancevska, Natalija and Karadelev, Mitko and Uzunoska, Zora and Kungulovski, Dzoko (2019) Evaluation of bactericidal activity of selected wild macrofungi extracts against Escherichia coli. Journal of Agriculture and Plant Sciences, 17 (2). pp. 53-57.

Full text not available from this repository.


The increasing failure of chemotherapeutics and antibiotic resistance exhibited by pathogenic
microorganisms has led to the evaluating of novel sources for their antimicrobial potential. Nature is a
generous source of compounds with antimicrobial activity. However, a large number of natural products with
the potential to act as antimicrobials still await further investigation. In this study, antimicrobial activities of
the extracts from four wild mushrooms: Amanita echinocephala, Russula medulata, Ishnoderma benzoinum
and Laetiporus sulphureus were evaluated against Gram-negative bacterium Escherichia coli. The antimicrobial
potential of the methanolic mushroom extracts was investigated by the microdilution method. Mild inhibitory
activity was observed in 3 out of 4 mushroom species included in the study. The extracts were further tested
for bactericidal activity and minimum bactericidal concentration (MBC) values were determined. The tested
microorganism was most sensitive to the examined extracts of Laetiporus sulphureus (MBC=62.5 mg/mL).
Even though the results revealed in this study may suggest that tested wild macrofungi extracts possess
mild antimicrobial activity, their antimicrobial potential against other microorganisms need to be further

Key words: mushroom, antimicrobial activity, microdilution method, minimum bactericidal concentration

Item Type: Article
Subjects: Scientific Fields (Frascati) > Agricultural Sciences > Animal and diary science
Scientific Fields (Frascati) > Engineering and Technology > Other engineering and technologies
Divisions: Faculty of Technology and Technical Sciences
Depositing User: Mr Jordan Martinovski
Date Deposited: 04 Jul 2023 11:53
Last Modified: 04 Jul 2023 11:53
URI: https://eprints.uklo.edu.mk/id/eprint/8561

Actions (login required)

View Item View Item