The gender difference and correlations of Neutrophil-to- Lymphocyte Ratio and D-dimer among hospitalized patients with COVID-19 in North Macedonia

Ilkovska, Biljana and Kotevska - Trifunova, Biljana and Avramovski, Petar (2022) The gender difference and correlations of Neutrophil-to- Lymphocyte Ratio and D-dimer among hospitalized patients with COVID-19 in North Macedonia. ОБЩА МЕДИЦИНА, 24 (6). pp. 66-71.

Text 29. === Обшта медицина Софиа - The gender deifference to NLymp ratio and d-dimer in Covid-19.pdf Download (335kB)

Abstract

Abstract. Introduction: Coronavirus disease has had a catastrophic effect on the world’s demographics,
resulting in more than 5.8 million deaths worldwide and more than 422 million confirmed cases reported
globally. The aim of this study was to assess the utility of the neutrophil-lymphocyte ratio (NLR), a simple,
widely available, and inexpensive laboratory examination, as a reliable inflammatory biomarker for COVID-19
patients. By comparing the NLR with the D-dimer plasma level, we also want to analyze gender differences
between hematological and hemostatic parameters in patients with COVID-19. Methods: This study was
carried in 2021 in Public Health Organization Clinical Hospital “Dr. Trifun Panovski” in Bitola in 2021. Our
study describes the laboratory characteristics of 40 COVID-19 patients hospitalized in the Department of
infective diseases. Results: The overall mean count of white blood cells count was 9 ± 0.28 x 109. The
overall mean of NLR was 9.3 ± 5.6. The overall mean of CRP and D-dimer was 58.7 ± 41.22 mg/l and 5624
± 1944 FEU ng/ml, respectively. NLR, CRP and D-dimer in the male and female groups in patients with
COVID-19 did not show statistically significant differences. We confirmed a significant correlation between
NLR and D-dimer levels in patients with COVID-19. Conclusion: NLR was found to correlate well with
the established inflammatory marker CRP and coagulation marker D-Dimer, which is capable of predicting
severe COVID-19. Therefore, NLR that is easily calculated at the emergency department using routine
laboratory tests, even in a remote area, may serve as a practical and cost-effective marker for guiding the
physician in awareness regarding the need for intensive care.
Key words: neutrophil-lymphocyte ratio, NLR, D-dimer, COVID-19

Item Type:	Article
Subjects:	Scientific Fields (Frascati) > Medical and Health Sciences > Clinical medicine
Divisions:	Rectorate
Depositing User:	D-r Petar Avramovski
Date Deposited:	13 Apr 2023 12:53
Last Modified:	13 Apr 2023 12:53
URI:	https://eprints.uklo.edu.mk/id/eprint/8010

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