Jasovic, V. and Jasovic Siveska, Emilija (2012) Uspeh intrauterusne inseminacije kod bolesnica sa nepoznatim uzrokom neplodnosti / Success rate of intrauterine insemination in patients with unknown infertility. Vojnosanitetski pregled: Military Medical & Pharmaceutical Journal of Serbia, 69 (4). pp. 301-307.
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Abstract
Background/Aim. Unknown cause of infertility exists in
10%–26% of couples with infertility problems. Treatment of
these couples depends on the posibility of correcting the
unidentified defect over time. Intrauterine insemination (IUI)
and ovaluation stimulation are methods of choice in treatment
of unexplained fertility, but if a woman is older than 37
years, in vitro fertilization (IVF) could be directly recommended.
The aim of this research was to compare the success
rate of pregnancies with IUI between the patients with unexplained
infertility and the patients with mild form endometriosis.
Methods. The study included on 50 patients diagnosed
with mild form endometriosis (group A) and 50 patients
with unknown cause infertility (group B). Using the
same therapeutical protocol, human menopausal gonadothropin
(hMG) stimulation and horionic gonadropin (hCG)
induction were applied, as well as IUI. Results. The percentage
of achieved ovulation was higher in the group B (p <
0.05). During the 3 simulated sequential periods 102 IUI were
performed in the group A and 97 IUI in the group B. In the
group A there were 6 single and 1 twin pregnancies sucesfully
conceived (14%), while in group B there were 9 (18%) single
pregnancies. Conclusion. The use of a combination of controled
ovarian hyperstimulation and IUI is an effective, cheap
and safe method for treating infertility couples, especially
couples with unknown cause infertility. Mild form endometriosis,
as etiological infertility factor, has a negative impact on
IUI success rate.
| Item Type: | Article |
|---|---|
| Subjects: | Scientific Fields (Frascati) > Medical and Health Sciences > Other medical sciences |
| Divisions: | Higher Medical School |
| Depositing User: | Vms Eprints |
| Date Deposited: | 23 May 2020 22:40 |
| Last Modified: | 23 May 2020 22:40 |
| URI: | https://eprints.uklo.edu.mk/id/eprint/5262 |
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