CRISPR-Cas-Based Genome Editing for Crop Improvement: Progress, Challenges and Future Prospects

Ntsomboh-Ntsefong, Godswill and Getachew Seyum, Essubalew and Mbi Kingsley, Tabi and Chekole Kassie, Fentanesh and Somo Toukam Gabriel, Mahbou and Karapetkovska Hristova, Vesna (2023) CRISPR-Cas-Based Genome Editing for Crop Improvement: Progress, Challenges and Future Prospects. Global Journal of Botanical Science, 11. pp. 38-43. ISSN E-ISSN: 2311-858X/23

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Abstract

Abstract: The discovery of the CRISPR-Cas genome editing technology has opened up new opportunities for crop
improvement through precise genetic modifications. This new technology has shown great promise in improving crop
yields, quality, and resilience to biotic and abiotic stresses. This review presents the recent advances in CRISPR-Cas
technology, including new tools and techniques for precise genome editing, as well as the challenges associated with
off-target effects and unintended consequences. It explores the applications of CRISPR-Cas-based genome editing in
different crops, including maize, rice, wheat, and tomato, highlighting the progress achieved in improving important traits
such as disease resistance, drought tolerance, and nutrient content. The regulatory concerns around CRISPR-Cas
based genome editing, as well as the ethical considerations associated with this technology are also adressed. Finally,
insights into the potential impact of CRISPR-Cas-based genome editing on crop breeding and food security, and the
challenges that need to be addressed to fully realize its potential are provided. This review thus highlights the potential of
CRISPR-Cas-based genome editing in crop improvement and emphasizes the importance of continued research in this
area for sustainable agricultural production.
Keywords: CRISPR-Cas, Genome editing, Crop improvement, Progress, Challenges, Future prospects.

Item Type:	Article
Subjects:	Scientific Fields (Frascati) > Agricultural Sciences > Agricultural biotechnology
Divisions:	Faculty of Biotechnical Sciences
Depositing User:	prof. d-r Vesna Karapetkovska-Hristova
Date Deposited:	12 Feb 2025 13:20
Last Modified:	12 Feb 2025 13:20
URI:	https://eprints.uklo.edu.mk/id/eprint/10625

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