Pulmonary Stasis or Metastases Spreading in Patients with Congestive Heart Failure

Avramovski, Petar and Mladenovska, Mira and Avramovska, Maja and Siljanovski, Simeon and Gjurovska, Tanja and Nikleski, Zorica and Sikole, Emilija (2019) Pulmonary Stasis or Metastases Spreading in Patients with Congestive Heart Failure. EC Pulmonology and Respiratory Medicine, 8 (12). pp. 1-5.

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Endometrial carcinoma (EC) as the most common gynecologic malignancy of the female genital tract which is commonly spreading
through pelvic lymph node and paraaortic lymph node or adnexa and pelvic viscera to pulmo, rectum, ovaries, fallopian tubes
and to bladder. Chest radiography is the initial imaging modality used in the detection of suspected pulmonary metastasis, but chest
computed tomography (CT) scanning without contrast is more sensitive than chest radiography. Metastatic spreading of EC into the
lung are rare cases, like ours case report, when pulmonary metastases are a random finding of previously unknown EC. We present
the case of 64 ages women with symptoms of congestive heart failure and several comorbidities, hypertension, hypothyreosis and
uterine fibroids. The heart decompensation and increased risk of atherosclerotic disease were confirmed by chest X-ray radiography
and these subsequent markers: brain natriuretic peptide (BNP) = 14838 pg/mL and homocysteine = 31.5 μmol/L. Elevated level of
CA 125 tumor marker (332.5 U/mL) and normal levels of another tumor markers: CA 15.3, CA 19.9, cytokeratin 19 fragments (CYFRA
21-1), CEA and AFP were laboratory confirmed. There was an evident increase in D-dimer (3060 to 6490 ng/ml) in two days.
Pulmonary metastasis and feeding vessel sign and pleurosis calcare was found on CT scan presented as soft tissue attenuation, well
circumscribed, rounded lesion in the lung periphery with feeding vessel sign as a prominent pulmonary vessel into metastasis. We
conclude that CT scan estimation is very important for early detection of metastatic dissemination in patients with positive history.
Keywords: Endometrial Carcinoma (EC); Computed Tomography (CT)

Item Type: Article
Subjects: Scientific Fields (Frascati) > Medical and Health Sciences > Clinical medicine
Divisions: UKLO Network
Depositing User: UKLO Mrezha
Date Deposited: 27 May 2024 06:04
Last Modified: 27 May 2024 06:04
URI: https://eprints.uklo.edu.mk/id/eprint/9926

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