Ilkovska, Biljana and Kotevska-Trifunova, Bisera (2013) Leptin level, body mass index and lipid parameters in children of Republic of Macedonia. Physioacta, 7 (3). pp. 79-85.
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Abstract
Objective:Leptin an important signal in the regulation of adipose-tissue mass and body weight, operates by inhibiting food intake and stimulating energy expenditure. Overweight and obese youth are at increased risk for premature cardiovascular disease. It's well known that the development of atherosclerosis begins in childhood and is accelerated in the presence of obesity. Leptin plays an important role in the pathogenesis of obesity.
Results: Serum leptin levels were higher in overweight boys and girls compared to normal weight boys and girls respectively(< 0.001;p<0.001). serum leptin positively correlated with BMI in all examinate groups. Triglycerides were significantly higher in overweight boys compared to normal weight boys (p<0.08). Overweight girls had significantly higher LDL cholesterol (p<0.006) and significant lower HDL cholesterol (p<0.004) than normal weight girls.
Conclusion: Overweight boys and girls had higher leptin levels. The BMI showed a high correlation with leptin levels in all examinate groups which suggest that BMI is the main indicator for the variation of leptin level. The concentration of LDL and HDL cholesterol differed only in the group of girls and tryglicerides in the group of boys.
| Item Type: | Article |
|---|---|
| Subjects: | Scientific Fields (Frascati) > Medical and Health Sciences > Basic medicine Scientific Fields (Frascati) > Medical and Health Sciences > Health sciences |
| Divisions: | UKLO Network |
| Depositing User: | UKLO Mrezha |
| Date Deposited: | 30 Jan 2024 08:04 |
| Last Modified: | 30 Jan 2024 08:04 |
| URI: | https://eprints.uklo.edu.mk/id/eprint/9331 |
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