General Stress Response of Salmonella enterica Typhimurium to Environmental Stress

Arapcheska, Mila and Tuteska, Jovanka and Jolivet-Gougeon, Anne (2020) General Stress Response of Salmonella enterica Typhimurium to Environmental Stress. In: EuroMicropH 1st Open Meeting, Lisbon, Portugal.

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Salmonella enterica Typhimurium is an enteric pathogen and etiological agent in bacterial food-borne diseases. The ability of Salmonella to survive in the food chain is due, in part, to its ability to respond effectively to environmental changes. S. enterica Typhimurium response to wide variety of environmental stresses is a result of highly complex and tightly regulated process of gene expression. The stress-induced changes in S. enterica Typhimurium bacterial cells were analyzed at the level of gene expression. For that purpose, the simultaneous analysis of gene expression of a set of 369 genes directly or indirectly involved in regulatory mechanisms and in virulence was performed by PCR-based microarray technique. Expression profile of bacterial cells submitted to oligotrophic stress (24 hours incubation in distilled water) was compared with expression profile of bacterial cells in exponential growth phase, considered as control condition. A number of induced genes under studied stress conditions, which ratio of gene expression (stress condition/control condition) had a value above 1.05 were genes that mediate in a general stress response. In fact, general stress response renders bacterial cells broadly stress resistant in a way in which damage is rather to be avoided than to be repaired.

Item Type: Conference or Workshop Item (Poster)
Subjects: Scientific Fields (Frascati) > Natural sciences > Biological sciences
Divisions: Faculty of Biotechnical Sciences
Depositing User: Prof. d-r Mila Arapceska
Date Deposited: 08 Mar 2021 21:12
Last Modified: 08 Mar 2021 21:12

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