Influence of niacin administration on lipid peroxidation in cows in early lactation.

HRISTOVSKA, TALIJA and CINCOVIĆ, MARKO and BELIĆ, BRANISLAVA and Djokovic, R and KOVAČEVIC, ZORANA and lakic, i (2018) Influence of niacin administration on lipid peroxidation in cows in early lactation. Acta agriculture serbica, XXIII (46). pp. 257-263.

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Niacin is a reactive part of NAD and NADP, which are co-enzymes in numerous oxidative and reductive reactions. In early lactation, there is an increased lipid mobilization, accompanied by inflammatory response and oxidative stress. The aim of this study was to examine the effect of niacin administration in cows during early lactation in reducing lipid peroxidation i.e. MDA (malondialdehyde) concentration. Niacin was administered through feed two weeks before and two weeks after calving. Blood samples were taken in the week preceding calving and in the first and second week after calving. MDA concentration was significantly lower in cows receiving niacin compared to the control group during all three samplings: 1.89±0.33:1.42±0.13 (calving, week 0); 2.37±0.41:1.64±0.15 (first week) and 2.6±0.45:1.8±0.17μmol/L (second week). In control cows, no significant correlation between MDA and NEFA concentrations was found compared to cows fed niacin. In cows receiving niacin, the concentration of MDA linearly increased, as did the NEFA concentration. Niacin supplementation in early lactation candecreaselipid peroxidation in cows. Reduced lipid peroxidation in cows can be a consequence of the antilipolytic effect of niacin.

Item Type: Article
Subjects: Scientific Fields (Frascati) > Agricultural Sciences > Veterinary science
Divisions: Faculty of Veterinary Medicine
Depositing User: Mr Aleksandar Lozanovski
Date Deposited: 04 Apr 2020 17:20
Last Modified: 04 Apr 2020 17:20

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